The next time you’re inclined to dump an artificial sweetner into your cup of joe, you might want to wait before you rip. That’s because natural sugars still tend to be the healthier choice, stresses one dietician.

Artificial sweeteners have been on the market for a long time, but there are still not enough long-term studies to determine safety and side effects of continued use.

So writes Emily DeLacey, M.S., R.D. for Fitday.com. The “top 4 most dangerous,” DeLacey writes, include some of the most common sweeteners on the market.

Flaws in the initial testing of acesuflame potassium (sold under the brand names Sweet One and Sunett) have been challenged by scientists in the Journal of the Environmental Health Perspectives, and they call for additional studies to be done to properly evaluate the safety of this sweetener.

DeLacey also discouraged excessive intake of aspartame, which the article stated is 200 times sweeter than table sugar, as well as saccharin (up to 700 times sweeter than table sugar) and  neotame (up to 13,000 times sweeter than table sugar).

 Choosing artificial sweeteners over plant-sourced sweeteners, like honey, has not actually been linked to long-term weight-loss and even in some cases there is more evidence that they are associated with increased weight gain. Sweeteners of any type should be always used in moderation. Eating whole foods with lots of fiber, vitamins, minerals and phytonutrients will help you better manage blood glucose levels and weight management goals. 

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